Worked fine with FSX and Prepar3D V2 when I had those installed. Not used FS2004 for a very long time, but I can't think of a reason why it wouldn't work.
Saying that, they all worked in Windows 8 and 8.1 for me. The only issue I had with FSX in Windows 8.1 was that after a while, my joystick would become unresponsive. CTRL+ALT+DEL then ESC would fix it, but it's not a great solution. This issue didn't exist in the tech preview of Windows 10.
Windows 10 is not based on Windows 7, it's not even based on Windows 8/8.1 particularly.
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Windows 10 compatibility for MSFS
Re: Windows 10 compatibility for MSFS
Just upgraded Windows 7 to Windows 10 with no issues, and it upgraded to Pro which was nice! 
Not got a flight simulator installed to test it though, sorry.
Not got a flight simulator installed to test it though, sorry.Who is online
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